Associate Research Specialist [email protected] Profiles Google Scholar Publications Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer's Disease. Directionality bias is necessary to explain spatiotemporal progression of pathology in mouse models of tauopathy. Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome. Cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease. Spatial cell-type enrichment predicts mouse brain connectivity. The effects of microglia on tauopathy progression can be quantified using Nexopathy in silico (Nexis) models. Connectome-based biophysics models of Alzheimer's disease diagnosis and prognosis. Matrix Inversion and Subset Selection (MISS): A pipeline for mapping of diverse cell types across the murine brain. Emergence of directional bias in tau deposition from axonal transport dynamics. Origins of atrophy in Parkinson linked to early onset and local transcription patterns. A method for inferring regional origins of neurodegeneration.
